First molecular approach to diagnose paediatric pulmonary lophomoniasis: A case series

Amirmasoud Taheri; Mahdi Fakhar; Maryam Nakhaei; Elham Sadat Banimostafavi; Farzad Masiha; Javad Ghaffari; Soroush Sheydai; Mohammad Sadegh Rezaei; Ali Sharifpour

doi:10.1002/rcr2.943

First molecular approach to diagnose paediatric pulmonary lophomoniasis: A case series

Respirol Case Rep. 2022 Mar 31;10(5):e0943. doi: 10.1002/rcr2.943. eCollection 2022 May.

Authors

Amirmasoud Taheri¹, Mahdi Fakhar¹, Maryam Nakhaei¹, Elham Sadat Banimostafavi^{1

2}, Farzad Masiha³, Javad Ghaffari³, Soroush Sheydai¹, Mohammad Sadegh Rezaei², Ali Sharifpour¹

Affiliations

¹ Toxoplasmosis Research Center, Communicable Diseases Institute Iranian National Registry Center for Lophomoniasis (INRCL), Mazandaran University of Medical Sciences Sari Iran.
² Radiology Department Iranian National Registry Center for Lophomoniasis (INRCL), Mazandaran University of Medical Sciences Sari Iran.
³ Department of Pediatrics, Pediatric Infectious Diseases Research Center Communicable Diseases Institute, Mazandaran University of Medical Sciences Sari Iran.

Abstract

A prospective study was conducted from 2017 to 2021 at Bouali Hospital in Mazandaran province, Sari, Iran. Out of 58 patients who were enrolled in our study, lophomoniasis was diagnosed in bronchoalveolar lavage fluid of nine patients, for the first time, using an in-house polymerase chain reaction technique. All patients were treated with metronidazole at 7.5 mg/kg/day every 12 h for 14 days. After 6 months of follow-up, symptoms were fully resolved.

Keywords: Lophomonas blattarum; PCR; lophomoniasis; paediatrics.

Publication types

Case Reports