Computer-Aided Recognition Based on Decision-Level Multimodal Fusion for Depression

IEEE J Biomed Health Inform. 2022 Jul;26(7):3466-3477. doi: 10.1109/JBHI.2022.3165640. Epub 2022 Jul 1.

Abstract

Aiming at the problem of depression recognition, this paper proposes a computer-aided recognition framework based on decision-level multimodal fusion. In Song Dynasty of China, the idea of multimodal fusion was contained in "one gets different impressions of a mountain when viewing it from the front or sideways, at a close range or from afar" poetry. Objective and comprehensive analysis of depression can more accurately restore its essence, and multimodal can represent more information about depression compared to single modal. Linear electroencephalography (EEG) features based on adaptive auto regression (AR) model and typical nonlinear EEG features are extracted. EEG features related to depression and graph metric features in depression related brain regions are selected as the data basis of multimodal fusion to ensure data diversity. Based on the theory of multi-agent cooperation, the computer-aided depression recognition model of decision-level is realized. The experimental data comes from 24 depressed patients and 29 healthy controls (HC). The results of multi-group controlled trials show that compared with single modal or independent classifiers, the decision-level multimodal fusion method has a stronger ability to recognize depression, and the highest accuracy rate 92.13% was obtained. In addition, our results suggest that improving the brain region associated with information processing can help alleviate and treat depression. In the field of classification and recognition, our results clarify that there is no universal classifier suitable for any condition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Brain / diagnostic imaging
  • China
  • Computers
  • Depression* / diagnosis
  • Electroencephalography* / methods
  • Humans