Community-Acquired Pneumonia

Ann Intern Med. 2022 Apr;175(4):ITC49-ITC64. doi: 10.7326/AITC202204190. Epub 2022 Apr 12.


Community-acquired pneumonia is an important cause of morbidity and mortality. It can be caused by bacteria, viruses, or fungi and can be prevented through vaccination with pneumococcal, influenza, and COVID-19 vaccines. Diagnosis requires suggestive history and physical findings in conjunction with radiographic evidence of infiltrates. Laboratory testing can help guide therapy. Important issues in treatment include choosing the proper venue, timely initiation of the appropriate antibiotic or antiviral, appropriate respiratory support, deescalation after negative culture results, switching to oral therapy, and short treatment duration.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19 Vaccines
  • COVID-19*
  • Community-Acquired Infections* / diagnosis
  • Community-Acquired Infections* / drug therapy
  • Humans
  • Pneumococcal Vaccines
  • Pneumonia* / diagnosis
  • Pneumonia* / drug therapy


  • COVID-19 Vaccines
  • Pneumococcal Vaccines