Phenotypes in Osteoarthritis: Why Do We Need Them and Where Are We At?

Murillo Dório; Leticia A Deveza

doi:10.1016/j.cger.2021.11.002

Phenotypes in Osteoarthritis: Why Do We Need Them and Where Are We At?

Clin Geriatr Med. 2022 May;38(2):273-286. doi: 10.1016/j.cger.2021.11.002.

Authors

Murillo Dório¹, Leticia A Deveza²

Affiliations

¹ Division of Rheumatology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Avendia Dr. Arnaldo 455, sala 3142, Cerqueira César, São Paulo, SP CEP 01246-903, Brazil. Electronic address: murillodorio@gmail.com.
² Rheumatology Department, Royal North Shore Hospital and Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Reserve Road, Sydney, New South Wales 2065, Australia.

PMID: 35410680
DOI: 10.1016/j.cger.2021.11.002

Abstract

This article is part of the Osteoarthritis issue for the Clinics in Geriatric Medicine journal. It covers the main aspects related to research and clinical practice of osteoarthritis phenotyping, including the concepts, the rationale for studies of OA phenotypes and their history, the approaches to OA phenotyping, recent advances in this area, and future directions.

Keywords: Endotypes; Machine learning; Osteoarthritis; Phenotypes.

Publication types

Review

MeSH terms

Aged
Forecasting
Humans
Osteoarthritis* / therapy
Phenotype