Enhancing prime editing efficiency by modified pegRNA with RNA G-quadruplexes

J Mol Cell Biol. 2022 Aug 2;14(4):mjac022. doi: 10.1093/jmcb/mjac022.

Xiangyang Li^{1

2}, Xin Wang^{1

2}, Wenjun Sun^{1

2}, Shisheng Huang^{1

2}, Mingtian Zhong³, Yuan Yao⁴, Quanjiang Ji⁵, Xingxu Huang^{1

6}

¹ Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
² University of Chinese Academy of Sciences, Beijing 100049, China.
³ Institute for Brain Research and Rehabilitation, Guangdong Key Laboratory of Mental Health and Cognitive Science, Center for Studies of Psychological Application, South China Normal University, Guangzhou 510631, China.
⁴ Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 311215, China.
⁵ School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
⁶ Guangzhou Laboratory, Guangzhou International Bio Island, Guangzhou 510005, China.

No abstract available

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