Purpose: To investigate the achieved optical zone and functional optical zone in myopic eyes with high astigmatism after small incision lenticule extraction (SMILE).
Methods: Seventy-five eyes of 75 consecutive patients with myopia before SMILE were included and divided into two groups (no astigmatism group: without astigmatism vs high astigmatism group: with astigmatism > 2.00 diopters). The achieved optical zone, functional optical zone, and corneal aberrations were compared using Scheimpflug imaging at 6 months postoperatively. Correlations between corneal aberrations and functional optical zone were analyzed.
Results: The mean achieved optical zone diameter was smaller in the no astigmatism group than in the high astigmatism group. There were no significant differences in achieved optical zone among the different meridians in each group. The mean functional optical zone diameter was significantly smaller in the no astigmatism group than in the high astigmatism group. Compared with the programmed optical zone, significant reduction of the functional optical zone was found in the two groups. The reduction of the functional optical zone was significantly smaller in the high astigmatism group than in the no astigmatism group, except for the 60°, 90°, and 120° meridians. There were significant correlations between the functional optical zone area and the induced corneal aberrations in the high astigmatism group, except for horizontal coma, whereas significant correlations of functional optical zone with total higher order aberrations and spherical aberration were detected in the no astigmatism group.
Conclusions: Myopic eyes with high astigmatism following SMILE had a circular achieved optical zone, but the functional optical zone was oval and larger than in eyes without astigmatism. Moreover, a lower spherical aberration was observed in the patients with high astigmatism. [J Refract Surg. 2022;38(4):243-249.].