Cutaneous allergic reaction correlates with anti-erythropoietin antibodies in dialysis patient developing pure red cell aplasia

Iuliana Badiu; Davide Diena; Giuseppe Guida; Carlo Ferrando; Davide Rapezzi; Luca Besso

doi:10.1002/ccr3.5554

Cutaneous allergic reaction correlates with anti-erythropoietin antibodies in dialysis patient developing pure red cell aplasia

Clin Case Rep. 2022 Apr 4;10(4):e05554. doi: 10.1002/ccr3.5554. eCollection 2022 Apr.

Authors

Iuliana Badiu¹, Davide Diena², Giuseppe Guida³, Carlo Ferrando², Davide Rapezzi⁴, Luca Besso²

Affiliations

¹ Mauriziano Hospital University Department of Allergology and Clinical Immunology Torino Italy.
² Clinical Department of Nephrology Santa Croce e Carle Cuneo Hospital Cuneo Italy.
³ Clinical Department of Allergology and Respiratory Physiopathology Santa Croce e Carle Cuneo Hospital Cuneo Italy.
⁴ Clinical Department of Haematology Santa Croce e Carle Cuneo Hospital Cuneo Italy.

Abstract

We describe a case of concomitant erythropoietin allergy and resistance with a possible IgE and IgG-mediated immune response, in which the local allergic cutaneous symptoms preceded the antibody-mediated anemia.

Keywords: allergy tests; anti‐erythropoietin antibodies; erythropoetin allergy; pure red cell aplasia.

Publication types

Case Reports