An specific photoelectrochemical sensor based on pillar[5]arenes functionalized gold nanoparticles and bismuth oxybromide nanoflowers for bovine hemoglobin recognition

Jin Wang; Lin Zhou; Jiali Bei; Mengyuan Xie; Xiting Zhu; Tingting Chen; Xiaomei Wang; Yukou Du; Yong Yao

doi:10.1016/j.jcis.2022.04.014

An specific photoelectrochemical sensor based on pillar[5]arenes functionalized gold nanoparticles and bismuth oxybromide nanoflowers for bovine hemoglobin recognition

J Colloid Interface Sci. 2022 Aug 15:620:187-198. doi: 10.1016/j.jcis.2022.04.014. Epub 2022 Apr 8.

Authors

Jin Wang¹, Lin Zhou², Jiali Bei², Mengyuan Xie², Xiting Zhu², Tingting Chen², Xiaomei Wang³, Yukou Du⁴, Yong Yao⁵

Affiliations

¹ School of Chemistry and Chemical Engineering, Nantong University, Nantong, 226019, PR China. Electronic address: wangjin107@ntu.edu.cn.
² School of Chemistry and Chemical Engineering, Nantong University, Nantong, 226019, PR China.
³ School of Chemical, Biology and Materials Engineering, Suzhou University of Science and Technology, Suzhou 215009, PR China. Electronic address: wangxiaomei@mail.usts.edu.cn.
⁴ College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, PR China. Electronic address: duyk@suda.edu.cn.
⁵ School of Chemistry and Chemical Engineering, Nantong University, Nantong, 226019, PR China. Electronic address: yaoyong1986@ntu.edu.cn.

PMID: 35421754
DOI: 10.1016/j.jcis.2022.04.014

Abstract

In this work, the ultrasensitive photoelectrochemical (PEC) sensor for the detection of bovine hemoglobin (BHb) was developed based on water-soluble pillar[5]arenes (WP5) functionalized gold nanoparticles (Au NPs) and bismuth oxybromide (BiOBr) nanoflowers (Au@WP5/BiOBr). The photoelectrical signal of dopamine (DA) was decreased after adding the different concentrations of BHb due to the formation of hydrogen bond between the COOH groups of BHb molecules and the NH₂ group of DA, which could achieve the indirect detection of BHb. Benefiting from the photo-generated electron-holes of BiOBr nanoflowers, the localized surface plasmon resonance (LSPR) effect of Au NPs, the host-guest interaction of WP5 between and DA, the PEC sensor showed a specificallyrecognize toward BHb with a wide detection range of 1.0 × 10^-11-1.0 × 10^-1 mg/mL and a detection limit of 4.2 × 10^-12 mg/mL (S/N = 3). Additionally, the proposed PEC sensor also displayed good stability, remarkable selectivity and provided a promising strategy of design pillar[5]arenes functionalized photoelectric activity nanomaterials for PEC sensing application.

Keywords: Au@WP5/BiOBr nanoflowers; Bovine hemoglobin; Dopamine; Photoelectrochemistry.

MeSH terms

Biosensing Techniques*
Bismuth / chemistry
Electrochemical Techniques
Gold / chemistry
Hemoglobins
Limit of Detection
Metal Nanoparticles* / chemistry

Substances

Hemoglobins
Gold
bismuth oxybromide
Bismuth