Candida glabrata is a successful pathogen: An artist manipulating the immune response

Microbiol Res. 2022 Jul:260:127038. doi: 10.1016/j.micres.2022.127038. Epub 2022 Apr 11.

Abstract

In recent years, Candida glabrata has emerged as a clinically important pathogen causing invasive infections and death. This review highlights the main virulence factors of this fungus and its strategies to subvert the cell response after invasion. Additionally, we emphasize the intracellular behavior and relationship of C. glabrata with several cells. We contrast these features with some fascinating strategies exhibited by M. tuberculosis to highlight that C. glabrata is a successful pathogen and an artist manipulating the immune response like M. tuberculosis.

Keywords: Candida glabrata; Mycobacterium tuberculosis; Successful pathogens; Virulence factors.

Publication types

  • Review

MeSH terms

  • Candida glabrata*
  • Humans
  • Immunity
  • Tuberculosis*