Early Identification of Chronic Mesenteric Ischemia with Endoscopic Duplex Ultrasound

Vasc Health Risk Manag. 2022 Apr 8;18:233-243. doi: 10.2147/VHRM.S358570. eCollection 2022.

Abstract

Introduction: Due to diagnostic delay, chronic mesenteric ischemia (CMI) is underdiagnosed. We assumed that the patients suspected of CMI of the atherosclerotic origin or median arcuate ligament syndrome (MALS) could be identified earlier with endoscopic duplex ultrasound (E-DUS).

Patients and methods: Fifty CMI patients with CTA-verified stenosis of either ≥50% and ≥70% of celiac artery (CA) and superior mesenteric artery (SMA) were examined with E-DUS and transabdominal duplex ultrasound (TA-DUS). Peak systolic velocities (PSV) of ≥200cm/s and ≥275cm/s for CA and SMA, respectively, were compared with CTA. Subgroup analysis was performed for the patients with (n=21) and without (n=29) prior revascularization treatment of CMI. The diagnostic ability of E-DUS and TA-DUS was tested with crosstabulation analysis. Receiver operating characteristics (ROC) curve analysis was performed, and the area under the curve (AUC) was calculated to investigate the test accuracy.

Results: In the patients with ≥70% stenosis, E-DUS had higher sensitivity than TA-DUS (91% vs 81% for CA and 100% vs 92% for SMA). AUC for SMA ≥70% in E-DUS was 0.75 and with TA-DUS 0.68. The sensitivity of E-DUS for CTA-verified stenosis ≥70% for CA was 100% in the patients without prior treatment. E-DUS demonstrated higher sensitivity than TA-DUS for both arteries with stenosis ≥50% and ≥70% in the treatment-naive patients.

Conclusion: E-DUS is equally valid as TA-DUS for the investigation of CMI patients and should be used as an initial diagnostic tool for patients suspected of CMI.

Keywords: MALS; acute mesenteric ischemia; chronic mesenteric ischemia; computed tomography angiography; duplex ultrasound; intestinal ischemia.

MeSH terms

  • Blood Flow Velocity
  • Constriction, Pathologic
  • Delayed Diagnosis
  • Humans
  • Ischemia / diagnostic imaging
  • Ischemia / therapy
  • Mesenteric Ischemia* / diagnostic imaging
  • Mesenteric Ischemia* / therapy
  • Retrospective Studies