New and emerging concepts and therapies for the treatment of food allergy

Immunother Adv. 2022 Feb 4;2(1):ltac006. doi: 10.1093/immadv/ltac006. eCollection 2022.


Food allergy is an increasingly common disease that often starts in early childhood and lasts throughout life. Self-reported food allergy has risen at a rate of 1.2% per decade since 1988, and by 2018, the prevalence of food allergy in the United States was estimated to be 8% in children and 11% in adults.- This prevalence has led to an economic burden of almost $25 billion annually. Despite these staggering statistics, as of the time of this writing, the Food and Drug Administration (FDA) has only approved one treatment for food allergy, which is limited to use in children with peanut allergy. Fortunately, a new horizon of therapeutic interventions, in all stages of development, lay ahead and hold promise for the near future.

Keywords: allergy and clinical immunology; immunotherapy; microbiome.

Publication types

  • Review