Left thalamic infarction and disturbance of verbal memory: a clinicoanatomical study with a new method of computed tomographic stereotaxic lesion localization

Ann Neurol. 1986 Dec;20(6):671-6. doi: 10.1002/ana.410200604.


A 41-year-old right-handed man developed disturbances of language and memory after a discrete thalamic infarction. Detailed neuropsychological assessment revealed deficits in verbal fluency, word finding, confrontation naming, and anterograde memory for verbal material. High-resolution computed tomography with stereotaxic lesion localization permitted the determination of the thalamic nuclei involved in the infarction. We suggest that the patient's problem in language and verbal memory reflected a defect in memory processing for verbal material during registration, retention, and retrieval, and that this defect probably resulted from a left anterior thalamic lesion affecting the ventrolateral nucleus, centromedian-parafascicular nuclei complex, internal medullary lamina, or mamillothalamic tract.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebral Infarction / complications*
  • Cerebral Infarction / diagnosis
  • Cerebral Infarction / diagnostic imaging
  • Humans
  • Language Disorders / diagnosis
  • Language Disorders / etiology*
  • Magnetic Resonance Spectroscopy
  • Male
  • Memory Disorders / diagnosis
  • Memory Disorders / etiology*
  • Psychological Tests
  • Stereotaxic Techniques*
  • Thalamus / blood supply*
  • Thalamus / diagnostic imaging
  • Tomography, X-Ray Computed / methods*