Respiratory effects of thyrotropin-releasing hormone and its analogue taltirelin on opioid-induced respiratory depression

Br J Anaesth. 2022 Jul;129(1):e4-e6. doi: 10.1016/j.bja.2022.03.022. Epub 2022 Apr 19.

Authors

Marijke H Algera¹, Joseph F Cotten², Monique van Velzen¹, Marieke Niesters¹, Martijn Boon¹, Daniel S Shoham², Kaye E Dandrea², Rutger van der Schrier¹, Albert Dahan³

Affiliations

¹ Department of Anesthesiology, Leiden University Medical Center, Leiden, the Netherlands.
² Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.
³ Department of Anesthesiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA. Electronic address: a.dahan@lumc.nl.

No abstract available

Keywords: electromyography; opioid-induced respiratory depression; respiratory depression; taltirelin; thyrotropin-releasing hormone.

Publication types

Letter

MeSH terms

Analgesics, Opioid / adverse effects
Humans
Respiratory Insufficiency* / chemically induced
Thyrotropin-Releasing Hormone* / pharmacology

Substances

Analgesics, Opioid
Thyrotropin-Releasing Hormone

Grants and funding

R21 DA045231/DA/NIDA NIH HHS/United States