JAK1/2 inhibitor but not IL-4 receptor alpha antibody suppresses allergen-mediated activation of human basophils in vitro

Allergy. 2022 Jul;77(7):2253-2256. doi: 10.1111/all.15322. Epub 2022 May 4.

Authors

Wenming Peng¹, Said Benfadal¹, Chunfeng Yu¹, Jörg Wenzel¹, Johannes Oldenburg², Natalija Novak¹

Affiliations

¹ Department of Dermatology and Allergy, University Hospital Bonn, Bonn, Germany.
² Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.

PMID: 35460281
DOI: 10.1111/all.15322

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Allergens*
Basophils*
Humans
Immunoglobulin E
Interleukin-13
Interleukin-4 Receptor alpha Subunit
Janus Kinase 1

Substances

Allergens
Interleukin-13
Interleukin-4 Receptor alpha Subunit
Immunoglobulin E
JAK1 protein, human
Janus Kinase 1