Abstract
A new model for evaluating nonsteroidal anti-inflammatory drugs (NSAIDs) is described. In this model of postoperative inflammation, the anti-inflammatory activity of curcumin (diferuloyl methane) was investigated in comparison with phenylbutazone and placebo. Phenylbutazone and curcumin produced a better anti-inflammatory response than placebo.
Publication types
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Clinical Trial
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Comparative Study
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Controlled Clinical Trial
MeSH terms
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Adolescent
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Adult
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Aged
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
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Catechols / therapeutic use*
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Clinical Trials as Topic
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Curcumin / therapeutic use*
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Double-Blind Method
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Humans
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Inflammation / drug therapy*
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Male
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Middle Aged
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Phenylbutazone / therapeutic use
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Postoperative Complications / drug therapy*
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Random Allocation
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Catechols
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Phenylbutazone
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Curcumin