Recurrent viral RNA positivity and candidiasis findings in hospitalized patients with COVID-19

Future Microbiol. 2022 Jun;17(9):673-682. doi: 10.2217/fmb-2022-0041. Epub 2022 Apr 25.

Abstract

Background: The aim of this study was to evaluate reinfection and fungal infections among 785 patients with COVID-19 disease admitted to Baqiyatallah Hospital in Northeastern Iran after the onset of the COVID-19 epidemic. Materials & Methods: In this descriptive-analytic study (20 February-21 July 2020), reinfection and fungal infections among 785 patients were investigated using epidemiological questionnaire, clinical trials, Real-time PCR and CT scan (chest computed tomography) from the hospital HIS (hospital's information system) and collected samples. Results: Reinfection and one oral candidiasis were diagnosed in one 68-year-old man and one 47-year-old man 63 and 42 days after the initial infection, respectively. Conclusion: The research results showed that exposure to COVID-19 may not establish long-term protective immunity to all patients.

Keywords: COVID-19; candidiasis; real-time PCR; reinfection.

Publication types

  • Case Reports

MeSH terms

  • COVID-19*
  • Candidiasis*
  • Humans
  • Male
  • Mycoses*
  • RNA, Viral / genetics
  • Reinfection

Substances

  • RNA, Viral