Over-the-scope-clip (OTSC®) as a rescue treatment for gastrointestinal bleeding secondary to peptic ulcer disease

Rev Esp Enferm Dig. 2023 Feb;115(2):70-74. doi: 10.17235/reed.2022.8722/2022.

Abstract

Background and aims: over-the-scope-clips (OTSC®) have been proposed as a rescue treatment for bleeding peptic ulcers. However, their effectiveness has not been evaluated in Spain.

Methods: this retrospective and single-center study (January 2018-December 2021) assessed the technical success, clinical success and safety of the device within 30 days. All patients with upper gastrointestinal bleeding due to a peptic ulcer and treated with the OTSC® clip (OVESCO) as a rescue therapy were included in the study.

Results: a total of eleven patients were included in the study, nine due to rebleeding and two due to persistent bleeding. Technical success was 81.9 % (9/11, confidence interval [CI] 95 %: 52-95 %). The per-protocol and intention-to-treat clinical success were 88.9 % (8/9, CI 95 %: 57-98 %) and 72.7 % (8/11, CI 95 %: 43-90 %), respectively. No device-related adverse effects were recorded.

Conclusion: the OTSC® clip was an effective and safe rescue therapy for bleeding peptic ulcers.

MeSH terms

  • Endoscopy, Gastrointestinal / methods
  • Gastrointestinal Hemorrhage / etiology
  • Gastrointestinal Hemorrhage / surgery
  • Hemostasis, Endoscopic* / adverse effects
  • Hemostasis, Endoscopic* / methods
  • Humans
  • Peptic Ulcer* / complications
  • Peptic Ulcer* / therapy
  • Retrospective Studies
  • Surgical Instruments
  • Treatment Outcome