Novel N,Cl-doped deep eutectic solvents-based carbon dots as a selective fluorescent probe for determination of morphine in food

Qinhong Yin; Mengtao Wang; Dong Fang; Yanqin Zhu; Lihua Yang

doi:10.1039/d1ra00886b

Novel N,Cl-doped deep eutectic solvents-based carbon dots as a selective fluorescent probe for determination of morphine in food

RSC Adv. 2021 May 7;11(27):16805-16813. doi: 10.1039/d1ra00886b. eCollection 2021 Apr 30.

Authors

Qinhong Yin¹, Mengtao Wang², Dong Fang², Yanqin Zhu³, Lihua Yang¹

Affiliations

¹ Faculty of Drug Control, Yunnan Police College Kunming 650223 China hawkyin2008@126.com.
² Faculty of Materials Science and Engineering, Kunming University of Science and Technology Kunming 650093 China.
³ Research Center for Analysis and Measurement, Kunming University of Science and Technology Kunming 650093 China.

Abstract

In the present study, new N,Cl co-doped carbon dots (N,Cl-CDs) based on deep eutectic solvent (DES) were fabricated by a facile hydrothermal process. This fluorescent probe exhibited a good quantum yield of 14% and was applied for the sensitive and selective quantification of morphine in foods. In addition, the influence of solution pH, interaction time, system temperature, interfering substances and analogues on the determination was also investigated. Under the optimized conditions, the luminescence intensity of carbon dots increased linearly with the addition of morphine in the concentration range of (0.15-280.25) μg mL^-1 (R ² > 0.9969) and the limit of detection (LOD) of 46.5 ng mL^-1. Based on these results, it is suggested that N,Cl-CDs is a promising fluorescent probe for sensitive and selective quantification of morphine in foods.