Objective: To observe the clinical curative effect of wentongzhenfa (warming and promoting technique of acupuncture) combined with extracorporeal shock wave in treatment of type Ⅲ prostatitis.
Methods: A total of 96 patients with type Ⅲ prostatitis were randomly divided into an observation group (48 cases) and a control group (48 cases). In the control group, the extracorporeal shock wave was combined with even-needling technique of acupuncture at Guanyuan (CV4), Mingmen (GV4), Zhongji (CV3), Zusanli (ST36), etc. In the observation group, the extracorporeal shock wave was combined with "warming and promoting technique" of acupuncture at the same acupoints as the control group. The treatment lasted 30 min each time, once daily in either group. There were 2 days of interval after consecutive treatment for 5 days. Totally, the duration of treatment was 1 month in two groups. The clinical curative effect was assessed after treatment. Before and after treatment, the changes in the concentrations of tumor nerosis factor-α (TNF-α), interleukin-1β(IL-1β) and IL-6 in prostatic fluid were determined; and the symptoms were scored, i.e. frequent, urgent and burning painful urine, difficulty in urination, dribbling urine, distending pain in perineum, bitter taste and dry mouth, and scrotal dampness. The changes in the scores of National Institute of Health chronic prostatitis symptom index (NIH-CPSI), international index of erectile function (IIEF), visual analogue scale (VAS) were evaluated befroe and after treatment. Successively, before treatment, after treatment, as well as 1 and 3 months after treatment, the quality of life was evaluated by Karnofsky in the patients of two groups.
Results: After treatment, the total effective rate was 89.6% (43/48) in the observation group, higher than 70.8% (34/48) in the control group (P<0.05). Compared with those before treatment, the concentrations of TNF-α and IL-1β in the prostatic fluid were all decreased (P<0.05) and the concentration of IL-6 was increased (P<0.05), the scores of symptoms, NIH-CPSI, IIEF and VAS were all reduced (P<0.05) in two groups. The changes of the above indexes were more obvious in the observation group than those in the control group (P<0.05). After treatment and 1 and 3 months after treatment, Karnofsky scores all increased (P<0.05) in two groups,and the increases were more significant in the observation group (P<0.05).
Conclusion: "Warming and promoting technique" of acupuncture combined with extracorporeal shock wave promotes the elimination of local inflammatory factors, relieves clinical symptoms, improves the quality of life, as well as has a satisfactory short-term and medium-term curative effect on type Ⅲ prostatitis.
目的:观察温通针法联合体外冲击波治疗Ⅲ型前列腺炎的临床疗效。方法:将96例确诊为Ⅲ型前列腺炎的患者随机分为观察组(48例)和对照组(48例)。对照组给予体外冲击波联合针刺关元、命门、中极、足三里等穴,观察组给予体外冲击波联合温通针法针刺治疗,选穴同对照组,均每次治疗30 min,每日1次,治疗5 d休息2 d,连续治疗1个月。治疗后评价两组临床疗效,检测前列腺液中肿瘤坏死因子(TNF)-α、白细胞介素(IL)-1β、IL-6含量的变化,评价治疗前后临床主要症状、慢性前列腺炎症状指数量表(NIH-CPSI)、国际勃起功能指数(IIEF)及视觉模拟量尺(VAS)评分变化,并于治疗前、治疗后及治疗后1、3个月评价两组患者的生活质量(KPS)。结果:治疗后观察组总有效率为89.6%(43/48),对照组总有效率为70.8%(34/48),观察组临床疗效优于对照组(P<0.05)。与治疗前比较,两组患者治疗后前列腺液中TNF-α、IL-1β含量降低(P<0.05),IL-6含量升高(P<0.05),NIH-CPSI、IIEF、VAS、临床主要症状评分均降低(P<0.05);观察组上述指标改善较对照组更明显(P<0.05)。两组治疗后及治疗后1、3个月,KPS评分升高(P<0.05),观察组升高更明显(P<0.05)。结论:温通针法联合体外冲击波治疗Ⅲ型前列腺炎,能促进前列腺局部炎性因子的排除,缓解临床症状,提高生活质量,并且短中期疗效良好。.
Keywords: Extracorporeal shock wave; Type Ⅲ prostatitis; “Warming and promoting technique” of acupuncture.