Lipidomics: An excellent tool for chronic disease detection

Curr Res Transl Med. 2022 Sep;70(4):103346. doi: 10.1016/j.retram.2022.103346. Epub 2022 Apr 26.


It has been known as almost all the cells consists a lipid molecule which has a considerable impact in various biological processes. Lipids have been investigated with a potential role for the formation of cellular membrane and thereby maintaining the structural integrity. Omics has placed as a combined technologies utilized for an exploaration of mechanistic actions in several kinds of molecules that make up the cells of an organism. Lipidomics has been recognized as a newly emerged branch of omics technology. This technology has the captivating factors to classify and characterize almost all the cellular lipids with the help of various analytical techniques and computational biological plateform. In lipidomics studies, structural display of several lipid biomarkers could also be analyzed and considered for actual disease diagnosis procedures. This could also replace certain traditional diagnostics method at all over the globe. Our review focuses how important this lipidomics particularly in disease diagnosis and also covers various analytical techniques and computational methods or bioinformatics tools in for the diagnosis of disease. In addtion, we also pinponted the possible role of lipids in several kinds of cellular disorders including cancer, neurodegenerative diseases, cardiovascular diseases, diabetes and obesity in human population. .

Keywords: Cellular disorders; Computational biology; Disease diagnosis; Lipidomics; Omics technology.

Publication types

  • Review

MeSH terms

  • Chronic Disease
  • Humans
  • Lipid Metabolism*
  • Lipidomics*
  • Lipids / chemistry
  • Mass Spectrometry / methods


  • Lipids