Right on target: The next class of efficient, safe, and specific RNAi triggers

Mol Ther Nucleic Acids. 2022 Apr 12:28:363-365. doi: 10.1016/j.omtn.2022.03.027. eCollection 2022 Jun 14.

Jonas Becker^{1

2}, Nico Fischer^{1

2}, Dirk Grimm^{1

3

4}

¹ Department of Infectious Diseases/Virology, Medical Faculty, University of Heidelberg, Center for Integrative Infectious Diseases Research (CIID), BioQuant, 69120 Heidelberg, Germany.
² Faculty of Biosciences, University of Heidelberg, 69120 Heidelberg, Germany.
³ German Center for Infection Research (DZIF), Partner Site Heidelberg, 69120 Heidelberg, Germany.
⁴ German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg, 69120 Heidelberg, Germany.

No abstract available

Keywords: RISC; RNA interference; RNAi; agshRNA; lentiviral vectors; miRNA; promoter; safety; shRNA; specificity.

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