ESMO 2021-highlights in colorectal cancer

Memo. 2022;15(2):114-116. doi: 10.1007/s12254-022-00808-7. Epub 2022 Apr 28.


This short review reflects on a personal selection of three abstracts on colorectal cancer (CRC) presented at the 2021 ESMO Congress: (1) KRASG12C as a new therapeutic target in metastatic CRC, supported by data from the KRYSTAL‑1 and CodeBreaK101 trials, (2) positive phase 3 data on the possible role of selective internal radiotherapy (SIRT) in the second-line treatment of liver-limited metastatic CRC, and (3) the impact of the coronavirus disease 2019 (COVID-19) pandemic on CRC screening, management and mortality, now and in the upcoming years.

Keywords: COVID-19; KRASG12C; SIRT; Treatment; Update.

Publication types

  • Review