Impact of quality improvement outreach education on the incidence of acute brain injury in transported neonates born premature

J Perinatol. 2022 Oct;42(10):1368-1373. doi: 10.1038/s41372-022-01409-2. Epub 2022 May 4.

Abstract

Objective: To evaluate impact of a quality improvement (QI) outreach education on incidence of acute brain injury in transported premature neonates.

Study design: Neonates born at <33 weeks gestation outside the tertiary center were included. The QI intervention was a combination of neuroprotection care bundle, in-person visits, and communication system improvement. Descriptive and regression (adjusting for Gestational Age, Birth Weight, Gender, and antenatal steroids, Mode of delivery, Apgars at 5 minutes, Prophylactic indomethacin, PDA, and Inotropes use) analyses were performed. The primary outcome was a composite of death and/or severe brain injury on cranial ultrasound using a validated classification.

Results: 181 neonates studied (93 before and 88 after). The rate and adjusted odds of death and/or severe brain injury reduced significantly post intervention (30% vs 15%) and (AOR 0.36, 95%CI, 0.15-0.85, P = 0.02) respectively.

Conclusion: Implementation of outreach education targeting neuroprotection can reduce acute brain injury in transported premature neonates.