Structural exploration of rhodium catalysts and their kinetic studies for efficient parahydrogen-induced polarization by side arm hydrogenation

Marino Itoda; Yuki Naganawa; Makoto Ito; Hiroshi Nonaka; Shinsuke Sando

doi:10.1039/c9ra02580d

Structural exploration of rhodium catalysts and their kinetic studies for efficient parahydrogen-induced polarization by side arm hydrogenation

RSC Adv. 2019 Jun 10;9(32):18183-18190. doi: 10.1039/c9ra02580d.

Authors

Marino Itoda¹, Yuki Naganawa^{1

2}, Makoto Ito¹, Hiroshi Nonaka¹, Shinsuke Sando^{1

3}

Affiliations

¹ Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-8656 Japan ssando@chembio.t.u-tokyo.ac.jp.
² Interdisciplinary Research Center for Catalytic Chemistry, National Institute of Advanced Industrial Science and Technology (AIST) 1-1-1 Higashi Tsukuba Ibaraki 305-8565 Japan yuki.naganawa@aist.go.jp.
³ Department of Bioengineering, Graduate School of Engineering, The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-8656 Japan.

Abstract

Parahydrogen-induced polarization (PHIP) is a rapid and cost-effective hyperpolarization technique using transition metal-catalysed hydrogenation with parahydrogen. We examined rhodium catalysts and their kinetic studies, rarely considered in the research of current PHIP. It emerged that rhodium complexes with electron-donating bisphosphine ligands, with a dicyclohexylphosphino group, appear to be more effective than conventional rhodium catalysts.