Gastric Perforation in a 60-Year-Old Woman with CMV Gastritis and Amphetamine Abuse Led to Death

Fatemeh Khajeh; Fatemeh Safari; Noorossadat Seyyedi; Fatemeh Asadian; Ali Farhadi; Abbas Behzad-Behbahani

doi:10.1159/000521719

Gastric Perforation in a 60-Year-Old Woman with CMV Gastritis and Amphetamine Abuse Led to Death

Case Rep Gastroenterol. 2022 Mar 25;16(1):129-134. doi: 10.1159/000521719. eCollection 2022 Jan-Apr.

Authors

Fatemeh Khajeh^{1

2}, Fatemeh Safari¹, Noorossadat Seyyedi¹, Fatemeh Asadian³, Ali Farhadi¹, Abbas Behzad-Behbahani¹

Affiliations

¹ Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
² Fasa University of Medical Sciences, Fasa, Iran.
³ Department of Medical Laboratory Sciences, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

Abstract

Gastric perforation as a multi-etiological disease is a full-thickness injury of the stomach wall. In this case report, we presented a 60-year-old woman with a history of suicidal behavior referred to the emergency unit with a decreased level of consciousness due to the multidrug consumption (amphetamine and benzodiazepine). Passing 3 days of admission in the intensive care unit, the patient represented severe abdominal distension, lack of defecation, and the absence of bowel sound, which suggested the gastrointestinal (GI) complication. Abdominal-pelvic sonography followed by laparotomy confirmed the gastric perforation, which finally led to the patient's death. Pathological analysis showed that the vast involvement of cytomegalovirus (CMV) in the patient's GI tract resulted in several peptic ulcers. The first report of gastric perforation-related death arises from the partnership of CMV infection and drug poisoning.

Keywords: Amphetamine; Cytomegalovirus infections; Intensive care units; Stomach diseases.

Publication types

Case Reports