COVID-19 during pregnancy and its impact on the developing auditory system

Am J Otolaryngol. 2022 Jul-Aug;43(4):103484. doi: 10.1016/j.amjoto.2022.103484. Epub 2022 May 4.

Abstract

Background: This study compared distortion product otoacoustic emissions (DPOAEs) and click-evoked auditory brainstem responses (ABRs) recorded from infants whose mother had Covid-19 during pregnancy (Covid-19 group) to infants whose mother did not have Covid-19 (Control group) during pregnancy.

Methods: This study retrospectively examined records of infants in the Covid-19 group (n = 15) and control group (n = 46) who had distortion product otoacoustic emissions (DPOAEs) and click-evoked auditory brainstem responses (ABRs) recorded as part of their clinical assessment. DPOAE amplitudes, absolute latencies (I, III, and V), and I-V interpeak intervals were examined.

Results: DPOAE amplitudes were similar between the Covid-19 group and the control group. The absolute latency of wave I was similar between groups. But absolute latencies III and V and I-V interpeak intervals of the Covid-19 group were significantly prolonged compared to the control group.

Conclusion: Covid-19 infection and its complications during pregnancy may not affect the cochlear function but may affect the functioning of the auditory brainstem.

Keywords: Auditory brainstem responses; Covid-19; Distortion product otoacoustic emissions.

MeSH terms

  • Auditory Threshold / physiology
  • COVID-19*
  • Evoked Potentials, Auditory, Brain Stem
  • Female
  • Humans
  • Infant
  • Otoacoustic Emissions, Spontaneous* / physiology
  • Pregnancy
  • Retrospective Studies