Does the History of Tracheoesophageal Fistula Repair Alter Outcomes of Laryngeal Cleft Repair?

Otolaryngol Head Neck Surg. 2023 Jan;168(1):39-44. doi: 10.1177/01945998221094210.


Objective: Tracheoesophageal fistula and esophageal atresia (TEA) and laryngeal cleft (LC) can coexist in some patients. The surgery-specific success rate of LC repair in children with associated TEA has not been well described. The aim of the study is to determine if the history of TEA alters the LC repair outcomes.

Study design: Case series with chart review.

Setting: Single-institution academic medical center.

Method: A retrospective review was conducted of patients with LC with and without TEA repair between January 2001 and November 2020. Data collected and analyzed included demographics and clinical characteristics, LC type, and LC with TEA timing of repairs.

Results: An overall 282 patients met the inclusion criteria of LC repair: LC (n = 242, 85.8%) and LC + TEA (n = 40, 14.2%). Revision repair was required in 43 patients (15.2%) with 8 (2.8%) needing a second revision repair. The first LC revision rate in the LC group was 36/242 (14.9%) as compared with 7/40 (17.5%) in the LC + TEA group (P = .67). The second LC revision rate in the LC and LC + TEA groups was 7 (2.9%) and 1 (2.4%), respectively. The median time to revision was 5.1 months (interquartile range, 3.45-10.6) in the LC group as compared with 29.2 months (interquartile range, 4.8-44.2) in the LC + TEA group (P = .06).

Conclusion: The incidence of TEA and LC was 14.2% in our study. Based on our findings, history of TEA repair is not associated with a higher revision rate vs LC alone. The history of TEA repair did not alter the outcomes of LC repair.

Keywords: laryngeal cleft; revision; tracheoesophageal fistula.

MeSH terms

  • Child
  • Esophageal Atresia* / complications
  • Esophageal Atresia* / epidemiology
  • Esophageal Atresia* / surgery
  • Humans
  • Incidence
  • Larynx* / abnormalities
  • Larynx* / surgery
  • Tracheoesophageal Fistula* / complications
  • Tracheoesophageal Fistula* / epidemiology
  • Tracheoesophageal Fistula* / surgery

Supplementary concepts

  • Laryngeal cleft