The repeatability and agreement of biometric measurements by dual Scheimpflug device with integrated optical biometer

Sci Rep. 2022 May 11;12(1):7748. doi: 10.1038/s41598-022-11953-8.


To determine the repeatability of biometric measurements by dual Scheimpflug Devices with Integrated Optical Biometers and its agreement with partial coherence interferometry according to the axial length (AL), and the presence of cataracts. The present population-based cross-sectional study was conducted on the geriatric population in Tehran. For participants, imaging was performed by dual Scheimpflug Devices with Integrated Optical Biometers (Galilei G6) and partial coherence interferometry (IOL Master 500). All measurements were performed by one person. In both normal and cataractous eyes, the ICC values were above 0.99 for three measurements of AL, intraocular lens (IOL) power target, anterior chamber depth (ACD), central corneal thickness (CCT), flat and steep keratometry readings, and mean total corneal power (MTCP). The repeatability coefficient for the AL measurements was 0.003 and 0.002 in eyes with and without cataracts, respectively. The mean difference of AL between IOL Master 500 and Galilei G6 in normal and cataractous eyes was 0.015 and -0.003 mm, respectively. The 95% limits of agreement (LoA) of AL between these two devices were -0.09 to 0.12 mm in normal and -0.09 to 0.08 mm in cataractous eyes. The 95% LoA of ACD between the two devices was -0.13 to 0.36 mm and -0.10 to 0.31 mm in eyes without and with cataracts, respectively. The 95% LoA of steep K between the two devices was -0.63 to 0.32 and -1.04 to 0.89 diopter in normal and cataractous eyes, respectively. The results of the present study indicate the high repeatability of Galilei G6 in ocular biometric measurements. Galilei biometric measurements, had a very high agreement with the IOL Master 500.

MeSH terms

  • Aged
  • Anterior Chamber / anatomy & histology
  • Anterior Chamber / diagnostic imaging
  • Axial Length, Eye* / anatomy & histology
  • Biometry
  • Cataract* / diagnosis
  • Cornea / anatomy & histology
  • Cross-Sectional Studies
  • Humans
  • Interferometry
  • Iran
  • Reproducibility of Results
  • Tomography, Optical Coherence / methods