Variant calling from scRNA-seq data allows the assessment of cellular identity in patient-derived cell lines
Nat Commun
.
2022 May 12;13(1):2718.
doi: 10.1038/s41467-022-30230-w.
Authors
Daniele Ramazzotti
1
,
Fabrizio Angaroni
2
,
Davide Maspero
2
3
,
Gianluca Ascolani
2
,
Isabella Castiglioni
4
,
Rocco Piazza
1
5
,
Marco Antoniotti
2
5
,
Alex Graudenzi
6
7
8
Affiliations
1
Dept. of Medicine and Surgery, Univ. of Milan-Bicocca, Monza, Italy.
2
Dept. of Informatics, Systems and Communication, Univ. of Milan-Bicocca, Milan, Italy.
3
Inst. of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Segrate, Milan, Italy.
4
Dept. of Physics "Giuseppe Occhialini", Univ. of Milan-Bicocca, Milan, Italy.
5
Bicocca Bioinformatics, Biostatistics and Bioimaging Centre - B4, Milan, Italy.
6
Dept. of Informatics, Systems and Communication, Univ. of Milan-Bicocca, Milan, Italy. alex.graudenzi@unimib.it.
7
Inst. of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Segrate, Milan, Italy. alex.graudenzi@unimib.it.
8
Bicocca Bioinformatics, Biostatistics and Bioimaging Centre - B4, Milan, Italy. alex.graudenzi@unimib.it.
PMID:
35551450
PMCID:
PMC9098403
DOI:
10.1038/s41467-022-30230-w
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
Comment
MeSH terms
Cell Line
Exome Sequencing
Gene Expression Profiling*
Humans
RNA-Seq
Sequence Analysis, RNA
Single-Cell Analysis*
Grants and funding
22790/CRUK_/Cancer Research UK/United Kingdom