Pediatric olfactory home testing using regular household items: A cross-over validation study

Int J Pediatr Otorhinolaryngol. 2022 Jul:158:111173. doi: 10.1016/j.ijporl.2022.111173. Epub 2022 May 6.

Abstract

Objective: To develop an olfactory test that can be conducted by an untrained person using common household items and to introduce a German version of the Chemosensory Pleasure Scale for Children (CPS-C(de)).

Methodology: This olfactory home test was developed in phases including evaluation of odors for suitability in a home setting. Parents of 50 children (ages 6-17) were then equipped with instruction manuals and participants were tested twice in a cross-over design. A validated pediatric olfactory test (the Universal Sniff test (U-Sniff)) served as the comparative gold standard. Additionally, a Chinese-English-German "back-and-forth" translation was conducted to establish the CPS-C(de) and was tested for empirical validity.

Results: Fourteen items were tested for feasibility, and all were identified on a sufficient rate (≥66%, mean ± SD of 93.3% ± 9.5%). Bland Altman Plot analysis between home testing and the U-Sniff test was nearly identical (bias = 0.04). CPS-C(de) showed similar results to the original Chinese version and a moderate correlation was found between CPS-C(de) scores and Body Mass Index of children (r30 = -0.527, p = 0.003).

Conclusions: Remote olfactory testing in children using household items is feasible. The CPS-C(de) may be of value for future olfactory studies.

Keywords: Anosmia; Covid-19; Hyposmia; Smell; U-sniff.

MeSH terms

  • Adolescent
  • Child
  • Cross-Over Studies
  • Humans
  • Odorants
  • Olfaction Disorders* / diagnosis
  • Sensory Thresholds
  • Smell