The migration of myogenic cells from the somites at the wing level in avian embryos

Dev Biol. 1987 Jun;121(2):389-96. doi: 10.1016/0012-1606(87)90175-8.


This study is concerned with establishing a morphological basis for the initiation of migration of putative myogenic cells from the somites into the presumptive wing bud in avian embryos. At the 22 somite stage (stage 14) vasculogenesis is a prevalent activity. By use of a quail specific monoclonal antibody to vascular endothelial cells, vascular cells are recognized in the lateral plate, on the intermediate mesoderm, and on somite surfaces. Cells that are found between the lateral plate mesoderm and somites are shown to be vascular endothelial cells. The lateral body folds progressively bring the lateral plate mesoderm close to the lateral margin of the somites and vascular elements disappear from surface view. It is not until the 24 somite stage (stage 15) that some cells in the ventral lateral margin of somites at the wing level can be seen in scanning electron micrographs to extend basal cell processes toward adjacent vascular tubes. These results provide a morphological basis for the early migratory behavior of myogenic cells and demonstrate their close proximity to the prepatterned vascular network.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cell Movement
  • Chick Embryo
  • Coturnix / embryology
  • Endothelium / cytology
  • Endothelium / embryology
  • Fluorescent Antibody Technique
  • Microscopy, Electron, Scanning
  • Muscles / blood supply
  • Muscles / cytology
  • Muscles / embryology*
  • Wings, Animal / cytology
  • Wings, Animal / embryology