Pulmonary hypertension in pregnancy and its effects on the fetus

Semin Fetal Neonatal Med. 2022 Aug;27(4):101348. doi: 10.1016/j.siny.2022.101348. Epub 2022 Apr 22.

Abstract

Pulmonary hypertension (PH) is an important and potentially lethal diagnosis for pregnant patients. Although pregnancy is usually contraindicated in this condition and there is no standard algorithm for the treatment of pregnant patients with PH, studies in recent years have shown improvement in maternal outcomes for those with PH. Many factors have likely contributed to the improved outcomes, including earlier treatment by multidisciplinary teams. Pregnant patients with PH require specialized management throughout pregnancy, especially in the early post-partum period. Echocardiography is an important diagnostic tool to follow cardiac function in these patients. PH and its treatment during pregnancy has significant implications on maternal as well as fetal outcomes. In this review, PH management during pregnancy and the fetal implications are summarized.

Keywords: High risk pregnancy; Perinatal mortality; Pulmonary hypertension.

Publication types

  • Review

MeSH terms

  • Echocardiography
  • Female
  • Fetus / diagnostic imaging
  • Humans
  • Hypertension, Pulmonary* / diagnosis
  • Hypertension, Pulmonary* / etiology
  • Pregnancy
  • Pregnancy Outcome
  • Prenatal Care