Female Urinary Retention Progressing to Possible Multiple System Atrophy-cerebellar Form after 12 Years

Ryuji Sakakibara; Yuki Sekiguchi; Jalesh N Panicker; Noritoshi Sekido; Hideki Sugimoto; Yuuka Sugisaki; Ayami Shimizu; Osamu Takahashi; Tsuyoshi Ogata; Setsu Sawai; Fuyuki Tateno; Yosuke Aiba; Sara Simeoni

doi:10.2169/internalmedicine.8724-21

Female Urinary Retention Progressing to Possible Multiple System Atrophy-cerebellar Form after 12 Years

Intern Med. 2022 Dec 1;61(23):3599-3604. doi: 10.2169/internalmedicine.8724-21. Epub 2022 May 14.

Authors

Affiliations

¹ Neurology, Internal Medicine, Sakura Medical Center, Toho University, Japan.
² Uro-gynecology, Female Medical Clinic 'Next Stage', Japan.
³ Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, UK.
⁴ Urology, Ohashi Medical Center, Toho University, Japan.
⁵ Neurology, Ohashi Medical Center, Toho University, Japan.
⁶ Urology, Sakura Medical Center, Toho University, Japan.
⁷ Clinical Physiology Unit, Sakura Medical Center, Toho University, Japan.

Abstract

We herein report a 73-year-old Japanese woman with possible multiple system atrophy-cerebellar form (MSA-C) who suffered from urinary retention (sacral autonomic disorder) for 12 years before exhibiting cerebellar ataxia. A peculiar combination of findings on urodynamics and sphincter electromyography (EMG), e.g. detrusor hyperactivity with impaired contraction (DHIC), detrusor-sphincter dyssynergia (DSD) and neurogenic sphincter EMG (upper and lower neuron-type autonomic dysfunction), seems to have been predictive of future development of MSA.

Keywords: magnetic resonance imaging; multiple system atrophy; sacral autonomic disorder; sphincter electromyography; urinary retention.

Publication types

Case Reports

MeSH terms

Aged
Autonomic Nervous System Diseases*
Cerebellum / diagnostic imaging
Electromyography
Female
Humans
Multiple System Atrophy* / complications
Multiple System Atrophy* / diagnosis
Urinary Bladder Diseases*
Urinary Retention* / etiology
Urodynamics