Cold atmospheric plasma for addressing the COVID-19 pandemic

Zhitong Chen; Fan Bai; Steven J Jonas; Richard E Wirz

doi:10.1002/ppap.202200012

Cold atmospheric plasma for addressing the COVID-19 pandemic

Plasma Process Polym. 2022 Sep;19(9):2200012. doi: 10.1002/ppap.202200012. Epub 2022 Apr 22.

Authors

Zhitong Chen^{1

2

3}, Fan Bai^{2

3}, Steven J Jonas^{4

5

6}, Richard E Wirz¹

Affiliations

¹ Department of Mechanical and Aerospace Engineering University of California, Los Angeles Los Angeles California USA.
² Advanced Therapy Center National Innovation Center for Advanced Medical Devices Shenzhen People's Republic of China.
³ Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen People's Republic of China.
⁴ Department of Pediatrics, David Geffen School of Medicine University of California, Los Angeles Los Angeles California USA.
⁵ California NanoSystems Institute University of California, Los Angeles Los Angeles California USA.
⁶ Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research University of California, Los Angeles Los Angeles California USA.

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has greatly stressed the global community, exposing vulnerabilities in the supply chains for disinfection materials, personal protective equipment, and medical resources worldwide. Disinfection methods based on cold atmospheric plasma (CAP) technologies offer an intriguing solution to many of these challenges because they are easily deployable and do not require resource-constrained consumables or reagents needed for conventional decontamination practices. CAP technologies have shown great promise for a wide range of medical applications from wound healing and cancer treatment to sterilization methods to mitigate airborne and fomite transfer of viruses. This review engages the broader community of scientists and engineers that wish to help the medical community with the ongoing COVID-19 pandemic by establishing methods to utilize broadly applicable CAP technologies.

Keywords: SARS‐CoV‐2 plasma disinfection; low temperature plasma (LTP); nonthermal plasma (NTP); plasma virus killing.

Publication types

Review

Grants and funding

DP5 OD028181/OD/NIH HHS/United States