The biological foundation of the Gompertz model

Int J Biomed Comput. 1987 Jan;20(1-2):35-9. doi: 10.1016/0020-7101(87)90012-2.


The paper examines the biological reasoning of the Gompertz model for tumor growth: the increase and loss rates of the tumor volume are both proportional to the volume itself. The statement is proved mathematically. The theoretical foundation is therefore established, this ensures the application of the Gompertz model as an effective aid for the understanding of the experimental and clinical tumor process.

MeSH terms

  • Animals
  • Humans
  • Models, Biological*
  • Models, Theoretical*
  • Neoplasms / pathology*