Tau: a phase in the crowd

EMBO J. 2022 Jun 1;41(11):e111425. doi: 10.15252/embj.2022111425. Epub 2022 May 17.

Abstract

From the management of microtubules to the production of pathological species: liquid-liquid phase separation may tune the behavior of the protein tau in health and neurodegenerative disease. In this issue of The EMBO Journal, Hochmair et al (2022) demystify important aspects of tau condensate compilation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Microtubules / metabolism
  • Neurodegenerative Diseases* / metabolism
  • tau Proteins / metabolism

Substances

  • tau Proteins