The gut microbiota: stable bioreactor of variable composition?

Gilles Mithieux

doi:10.1016/j.tem.2022.04.005

The gut microbiota: stable bioreactor of variable composition?

Trends Endocrinol Metab. 2022 Jul;33(7):443-446. doi: 10.1016/j.tem.2022.04.005. Epub 2022 May 16.

Author

Gilles Mithieux¹

Affiliation

¹ Institut National de la Santé et de la Recherche Médicale U1213 'Nutrition, Diabetes and the Brain', Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France. Electronic address: gilles.mithieux@inserm.fr.

PMID: 35584972
DOI: 10.1016/j.tem.2022.04.005

Abstract

The gut microbiota plays a crucial role in host health, providing energy and vitamins from food undigested by the gut enzymes of the host. Bacterial metabolites, such as short-chain fatty acids (SCFAs), are essentially metabolized by the gut mucosa. The importance to metabolic health of gut microbiota composition versus function is discussed.

Keywords: gut microbiota; intestinal gluconeogenesis; microbial metabolites; short-chain fatty acids.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bioreactors
Fatty Acids, Volatile / metabolism
Gastrointestinal Microbiome*
Humans

Substances

Fatty Acids, Volatile