Abstract
Nonsense mutations derived from 90 different codons in the lacI gene of Escherichia coli have been correlated with the I gene nucleotide sequence. In over 80 cases the specific codon which generates the nonsense mutation can be identified. The sequence shows that 14-16 sites arise through tandem double base changes.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Amino Acids / genetics
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Base Sequence
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Codon*
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Escherichia coli / genetics*
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Genes*
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Genes, Regulator*
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Lactose / genetics*
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Mutation
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Peptide Chain Termination, Translational
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RNA, Messenger*
Substances
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Amino Acids
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Codon
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RNA, Messenger
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Lactose
Associated data
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GENBANK/J01636
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GENBANK/J01637
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GENBANK/K01483
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GENBANK/K01793