Pain is an unpleasant sensory and psychological experience resulting from actual or potential tissue damage and is commonly associated with dental treatment. Local anesthesia is a safe and effective way of managing pain. Anesthetic agents work by reversibly binding to sodium channels, preventing the entry of sodium into the cells and thereby inhibiting the propagation of nerve impulses. Consequently, nociceptive impulses associated with painful stimuli do not reach the brain, and the patient does not perceive pain.
The maxillary and mandibular branches of the trigeminal nerve provide sensory innervation to the soft and hard tissues of the oral cavity. The anesthetic solution must be injected adjacent to the nerve supplying the area where dental treatment will be performed. A thorough understanding of these trigeminal nerve branches and associated anatomical landmarks is essential.
Local anesthesia in dentistry can be given as either infiltration or block anesthesia. Generally, infiltration anesthesia is commonly used in the maxilla, whereas block anesthesia is frequently used in the mandible. In addition, there are supplemental local anesthesia techniques that can be utilized when infiltration and block methods have failed to achieve profound anesthesia. Supplemental techniques include intraligamentary, intraosseous, intrapulpal, and interseptal anesthesia.
This paper will explore the anatomical course of the nerves supplying the oral cavity and the different techniques utilized to anesthetize these nerves prior to delivering dental treatment. The equipment required for dental local anesthesia, including common anesthetic agents and their applications, will be considered. Furthermore, the prevention and management of complications associated with local anesthesia will be discussed.
Copyright © 2025, StatPearls Publishing LLC.