Disc-fovea distance and choroidal thickness: is there a relationship?

Selim Cevher; Mehmet Barış Üçer; Tayfun Şahin

doi:10.1177/25158414221096062

Disc-fovea distance and choroidal thickness: is there a relationship?

Ther Adv Ophthalmol. 2022 May 15:14:25158414221096062. doi: 10.1177/25158414221096062. eCollection 2022 Jan-Dec.

Authors

Selim Cevher¹, Mehmet Barış Üçer², Tayfun Şahin³

Affiliations

¹ Assistant Professor of Ophthalmology, Department of Ophthalmology, Faculty of Medicine, Hitit University, 019040 Çorum, Turkey.
² Department of Ophthalmology, Minister of Health Hitit University Erol Olçok Education and Research Hospital, Çorum, Turkey.
³ Department of Ophthalmology, Faculty of Medicine, Hitit University, Çorum, Turkey.

Abstract

Background: The distance between the optic disc center and the fovea is a biometric parameter; however, it is unclear whether DFD (disc-fovea distance) affects the choroidal thickness.

Objective: The aim of this study is to investigate the association between DFD and choroidal thickness.

Design: This is a prospective, and cross-sectional study.

Methods: Two hundred fifty eyes of 250 healthy participants were examined in terms of DFD, age, axial length, spherical equivalent, and choroidal thickness. Inclusion criteria included aged between 20-40 years, no posterior segment disorders, and participants with best-corrected visual acuity (10/10 according to Snellen's chart). Participants with high hypermetropia (>4 diopter) or myopia (>6 diopter) or any systemic disease likely to affect choroidal thickness were excluded. Choroidal thickness measurements were performed at subfoveal, 1.0 mm temporal, and 1.0 mm nasal using the enhanced-depth imaging optical coherence tomography.

Results: The mean age of all the participants was 26.21 ± 5.73 years, mean DFD was 4634.29 ± 274.70 µm, mean axial length was 23.62 ± 0.83 mm, and mean spherical equivalent was -0.61 ± 1.06 diopter. The mean subfoveal, nasal, and temporal choroidal thicknesses were 388.73 ± 90.15 µm, 351.26 ± 88.09 µm, and 366.50 ± 79.56 µm, respectively. A negative correlation was found between subfoveal, nasal, and temporal choroidal thicknesses and axial length (r = -0.157, p = 0.013; r = -0.168, p = 0.008; r = -0.174, p = 0.006, respectively). Insignificant correlation was found between choroidal thicknesses and spherical equivalent (p > 0.05). There was not a statistically significant correlation between DFD and subfoveal, nasal, and temporal choroidal thicknesses (r = -0.028, p = 0.655; r = 0.030, p = 0.641; r = -0.025, p = 0.699, respectively). In addition, there was not a statistically significant correlation between age and choroidal thickness.

Conclusion: This study shows that DFD and spherical equivalent do not affect choroidal thickness; axial length negatively affects choroidal thickness. In addition, age does not affect choroidal thickness between 20 and 40 years.

Keywords: choroidal thickness; disc–fovea distance; enhanced-depth imaging optical coherence tomography; healthy participants.