Extensive macular atrophy with pseudodrusen-like: Case series and review

Eur J Ophthalmol. 2023 Jul;33(4):NP80-NP84. doi: 10.1177/11206721221102269. Epub 2022 May 23.

Abstract

Purpose: To describe the clinical characteristics of two patients affected by extensive macular atrophy with pseudodrusen-like (EMAP).

Methods: Two patients affected by EMAP underwent multimodal imaging, including fundus autofluorescence and optical coherence tomography.

Results: The patients showed the typical clinical appearance with macular atrophy with larger vertical axis surrounded by pseudodrusen-like deposits involving the midperiphery, associated with paving stone lesions in the retinal periphery.

Conclusion: EMAP is a complex condition sharing clinical characteristics of age-related macular degeneration. Further studies are warranted to identify the early biomarker of the disease.

Keywords: Extensive macular atrophy with pseudodrusen; fundus autofluorescence; geographic atrophy; macular atrophy.

Publication types

  • Case Reports

MeSH terms

  • Atrophy
  • Fluorescein Angiography
  • Fundus Oculi
  • Geographic Atrophy* / complications
  • Geographic Atrophy* / diagnosis
  • Humans
  • Macular Degeneration* / complications
  • Macular Degeneration* / diagnosis
  • Retina
  • Retinal Drusen* / diagnosis
  • Tomography, Optical Coherence / methods