Supported Palladium Nanoparticles Catalyzed Intermolecular Carbopalladation of Nitriles and Organoboron Compounds

Xin Liu; Dan Liu; Tegshi Muschin; Agula Bao; Chaolumen Bai; Yong-Sheng Bao

doi:10.3389/fchem.2022.855850

Supported Palladium Nanoparticles Catalyzed Intermolecular Carbopalladation of Nitriles and Organoboron Compounds

Front Chem. 2022 May 9:10:855850. doi: 10.3389/fchem.2022.855850. eCollection 2022.

Authors

Xin Liu¹, Dan Liu¹, Tegshi Muschin¹, Agula Bao¹, Chaolumen Bai¹, Yong-Sheng Bao¹

Affiliation

¹ Inner Mongolia Key Laboratory of Green Catalysis, College of Chemistry and Environmental Science, Inner Mongolia Normal University, Hohhot, China.

Abstract

The first heterogeneous catalyzed example for the direct synthesis of aromatic ketones via intermolecular carbopalladation of aliphatic nitriles and organoboron compounds was developed. This mild method proceeds with a supported palladium nanoparticles catalyst that could be reused and recycled five times. The fresh and used catalysts were characterized by XPS and TEM. The XPS analysis indicated that Pd⁰ was the active species for the reaction. This methodology provides a mild and cost-effective strategy for the efficient synthesis of ketones.

Keywords: aromatic ketones; carbopalladation; green chemistry; nitriles; supported palladium nanoparticles.