SARS-CoV-2 Infection Is Not Associated With Pediatric Appendicitis

Pediatr Infect Dis J. 2022 Aug 1;41(8):e321-e323. doi: 10.1097/INF.0000000000003575. Epub 2022 Jul 13.


Although case reports have suggested an association between severe acute respiratory distress syndrome coronavirus 2 and appendicitis, we found that the overall incidence of appendicitis was stable throughout the pandemic at our tertiary pediatric hospital. Furthermore, we did not find evidence of CoV2 infection in 9 appendicitis tissues. Therefore, we conclude that severe acute respiratory distress syndrome coronavirus 2 infection of the appendix is not a common etiologic cause of pediatric appendicitis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Appendicitis* / complications
  • Appendicitis* / epidemiology
  • COVID-19* / complications
  • Child
  • Humans
  • Pandemics
  • Respiratory Distress Syndrome*
  • SARS-CoV-2