Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19
Nat Immunol
.
2022 Jun;23(6):861-864.
doi: 10.1038/s41590-022-01227-w.
Epub 2022 May 27.
Authors
Michael Hultström
#
1
2
3
4
,
Robert Frithiof
#
1
,
Jonathan Grip
#
5
6
,
Linnea Lindelöf
#
7
,
Olav Rooijackers
5
6
,
Sara Pigazzini
8
,
Mari Niemi
8
,
Mattia Cordioli
8
,
Lindo Nkambule
8
,
Tomislav Maricic
9
,
Kristina Nilsson Ekdahl
7
10
,
Bo Nilsson
7
,
Miklós Lipcsey
1
11
,
Hugo Zeberg
#
12
13
,
Oskar Eriksson
#
14
Affiliations
1
Anesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
2
Integrative Physiology, Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
3
Department of Epidemiology, McGill University, Montréal, Quebec, Canada.
4
Lady Davis Institute of Medical Research, Jewish General Hospital, Montréal, Quebec, Canada.
5
Department of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.
6
Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
7
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
8
Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.
9
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
10
Linnaeus Center for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden.
11
Hedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
12
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. hugo.zeberg@ki.se.
13
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. hugo.zeberg@ki.se.
14
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. oskar.eriksson@igp.uu.se.
#
Contributed equally.
PMID:
35624204
DOI:
10.1038/s41590-022-01227-w
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
Comment
MeSH terms
COVID-19* / complications
COVID-19* / genetics
Genotype
Humans
Mannose-Binding Lectins
Substances
Mannose-Binding Lectins