Chronic Inflammatory Demyelinating Polyneuropathy Post-mRNA-1273 Vaccination

Cureus. 2022 Apr 27;14(4):e24528. doi: 10.7759/cureus.24528. eCollection 2022 Apr.

Abstract

Massive efforts are being made to develop coronavirus disease 2019 (COVID-19) vaccines at an unprecedented rate. The vaccinations' adverse impact profile, on the other hand, has not been well established. Neurological complications are increasingly reported as a result of these vaccines. One such complication identified is immune-mediated inflammatory polyneuropathy, which affects peripheral nerves and neurons. We report a case of chronic inflammatory demyelinating polyneuropathy (CIDP) post-mRNA-1273 (Moderna) COVID-19 vaccine. Recognizing this complication and distinguishing it from Guillain-Barré syndrome enables timely initiation of treatment. Additionally, our report highlights a possible link between vaccination and subsequent development of CIDP, but conclusive evidence of a causal relationship requires more extensive studies.

Keywords: chronic inflammatory demyelinating polyneuropathy (cidp); cidp; covid 19 vaccine complication; covid-19 vaccine; demyelinating disorder; demyelinating polyneuropathy; moderna; moderna mrna-1273; mrna-1273.

Publication types

  • Case Reports