Association Between COVID-19 Booster Vaccination and Omicron Infection in a Highly Vaccinated Cohort of Players and Staff in the National Basketball Association

doi:10.1001/jama.2022.9479

. 2022 Jul 12;328(2):209-211.

doi: 10.1001/jama.2022.9479.

Association Between COVID-19 Booster Vaccination and Omicron Infection in a Highly Vaccinated Cohort of Players and Staff in the National Basketball Association

Caroline G Tai¹, Lisa L Maragakis², Sarah Connolly¹, John DiFiori³, Deverick J Anderson⁴, Yonatan H Grad⁵, Christina DeFilippo Mack¹

Affiliations

¹ IQVIA, Durham, North Carolina.
² Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
³ National Basketball Association, New York, New York.
⁴ Duke Center for Antimicrobial Stewardship and Infection Prevention, Duke University School of Medicine, Durham, North Carolina.
⁵ Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.

PMID: 35653123
PMCID: PMC9164115
DOI: 10.1001/jama.2022.9479

Association Between COVID-19 Booster Vaccination and Omicron Infection in a Highly Vaccinated Cohort of Players and Staff in the National Basketball Association

Caroline G Tai et al. JAMA. 2022.

. 2022 Jul 12;328(2):209-211.

doi: 10.1001/jama.2022.9479.

Authors

Caroline G Tai¹, Lisa L Maragakis², Sarah Connolly¹, John DiFiori³, Deverick J Anderson⁴, Yonatan H Grad⁵, Christina DeFilippo Mack¹

Affiliations

¹ IQVIA, Durham, North Carolina.
² Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
³ National Basketball Association, New York, New York.
⁴ Duke Center for Antimicrobial Stewardship and Infection Prevention, Duke University School of Medicine, Durham, North Carolina.
⁵ Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.

PMID: 35653123
PMCID: PMC9164115
DOI: 10.1001/jama.2022.9479

Abstract

This study compares the incidence of SARS-CoV-2 infection in players and staff of the National Basketball Association (NBA) who did vs those who did not receive a COVID-19 vaccine booster dose.

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Conflict of interest statement

Conflict of Interest Disclosures: Drs Tai, Connolly, and Mack are employees of IQVIA, which is in a paid consultancy with the National Basketball Association (NBA). Dr Maragakis reported receiving support from the US Centers for Disease Control and Prevention (CDC) and the Agency for Healthcare Research and Quality; receiving personal fees while serving as a paid consultant to the NBA; and serving as a co-chair of the Healthcare Infection Control Practices Advisory Committee of the CDC. Dr DiFiori reported receiving consulting fees from the NBA. Dr Anderson reported receiving institutional support from the CDC, the Agency for Healthcare Research and Quality, and the National Institute of Allergy and Infectious Diseases; receiving royalties from Up To Date; and ownership of Infection Control Education for Major Sports. Dr Grad reported receiving support from the National Institutes of Health, the Smith Family Foundation, Welcome Trust, Pfizer, and Merck; receiving consulting fees from GlaxoSmithKline, Quidel, and the NBA; receiving payment for expert testimony from Merck; having a provisional patent application for Neisseria gonorrhoeae therapies; and serving on the scientific advisory board for Day Zero Diagnostics. No other disclosures were reported.

Comment in

Association Between COVID-19 Booster Vaccination and Omicron Infection in a Cohort of Players and Staff in the National Basketball Association.
Manmadhan A, Ahuja T. Manmadhan A, et al. JAMA. 2022 Dec 6;328(21):2164-2165. doi: 10.1001/jama.2022.18034. JAMA. 2022. PMID: 36472599 No abstract available.

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References

1. Johnson AG, Amin AB, Ali AR, et al. . COVID-19 incidence and death rates among unvaccinated and fully vaccinated adults with and without booster doses during periods of Delta and Omicron Variant Emergence—25 US jurisdictions, April 4-December 25, 2021. MMWR Morb Mortal Wkly Rep. 2022;71(4):132-138. doi:10.15585/mmwr.mm7104e2 - DOI - PMC - PubMed
1. Thompson MG, Natarajan K, Irving SA, et al. . Effectiveness of a third dose of mRNA vaccines against COVID-19–associated emergency department and urgent care encounters and hospitalizations among adults during periods of Delta and Omicron variant predominance—VISION Network, 10 states, August 2021-January 2022. MMWR Morb Mortal Wkly Rep. 2022;71(4):139-145. doi:10.15585/mmwr.mm7104e3 - DOI - PMC - PubMed
1. Accorsi EK, Britton A, Fleming-Dutra KE, et al. . Association between 3 doses of mRNA COVID-19 vaccine and symptomatic infection caused by the SARS-CoV-2 Omicron and Delta variants. JAMA. 2022;327(7):639-651. doi:10.1001/jama.2022.0470 - DOI - PMC - PubMed
1. US Centers for Disease Control and Prevention . Stay up to date with your vaccines. Accessed April 10, 2022. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html
1. Andersen PK, Gill RD. Cox’s regression model for counting processes: a large sample study. Ann Stat. 1982;10(4):1100-1120. doi:10.1214/aos/1176345976 - DOI

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[1] Johnson AG, Amin AB, Ali AR, et al. . COVID-19 incidence and death rates among unvaccinated and fully vaccinated adults with and without booster doses during periods of Delta and Omicron Variant Emergence—25 US jurisdictions, April 4-December 25, 2021. MMWR Morb Mortal Wkly Rep. 2022;71(4):132-138. doi:10.15585/mmwr.mm7104e2 - DOI - PMC - PubMed

[2] Johnson AG, Amin AB, Ali AR, et al. . COVID-19 incidence and death rates among unvaccinated and fully vaccinated adults with and without booster doses during periods of Delta and Omicron Variant Emergence—25 US jurisdictions, April 4-December 25, 2021. MMWR Morb Mortal Wkly Rep. 2022;71(4):132-138. doi:10.15585/mmwr.mm7104e2 - DOI - PMC - PubMed

[3] Thompson MG, Natarajan K, Irving SA, et al. . Effectiveness of a third dose of mRNA vaccines against COVID-19–associated emergency department and urgent care encounters and hospitalizations among adults during periods of Delta and Omicron variant predominance—VISION Network, 10 states, August 2021-January 2022. MMWR Morb Mortal Wkly Rep. 2022;71(4):139-145. doi:10.15585/mmwr.mm7104e3 - DOI - PMC - PubMed

[4] Thompson MG, Natarajan K, Irving SA, et al. . Effectiveness of a third dose of mRNA vaccines against COVID-19–associated emergency department and urgent care encounters and hospitalizations among adults during periods of Delta and Omicron variant predominance—VISION Network, 10 states, August 2021-January 2022. MMWR Morb Mortal Wkly Rep. 2022;71(4):139-145. doi:10.15585/mmwr.mm7104e3 - DOI - PMC - PubMed

[5] Accorsi EK, Britton A, Fleming-Dutra KE, et al. . Association between 3 doses of mRNA COVID-19 vaccine and symptomatic infection caused by the SARS-CoV-2 Omicron and Delta variants. JAMA. 2022;327(7):639-651. doi:10.1001/jama.2022.0470 - DOI - PMC - PubMed

[6] Accorsi EK, Britton A, Fleming-Dutra KE, et al. . Association between 3 doses of mRNA COVID-19 vaccine and symptomatic infection caused by the SARS-CoV-2 Omicron and Delta variants. JAMA. 2022;327(7):639-651. doi:10.1001/jama.2022.0470 - DOI - PMC - PubMed

[7] US Centers for Disease Control and Prevention . Stay up to date with your vaccines. Accessed April 10, 2022. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html

[8] US Centers for Disease Control and Prevention . Stay up to date with your vaccines. Accessed April 10, 2022. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html

[9] Andersen PK, Gill RD. Cox’s regression model for counting processes: a large sample study. Ann Stat. 1982;10(4):1100-1120. doi:10.1214/aos/1176345976 - DOI

[10] Andersen PK, Gill RD. Cox’s regression model for counting processes: a large sample study. Ann Stat. 1982;10(4):1100-1120. doi:10.1214/aos/1176345976 - DOI

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Association Between COVID-19 Booster Vaccination and Omicron Infection in a Highly Vaccinated Cohort of Players and Staff in the National Basketball Association

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Association Between COVID-19 Booster Vaccination and Omicron Infection in a Highly Vaccinated Cohort of Players and Staff in the National Basketball Association

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