Spontaneous coronary artery dissection occurs with and without periadventitial inflammation

Arch Pathol Lab Med. 1987 May;111(5):470-2.


Dissection of a coronary artery not associated with aortic dissection or trauma is a rare condition that occurs most frequently in peripartum or postpartum women. It has been suggested that localized periadventitial inflammation, often found adjacent to these lesions, may represent a primary vasculitis which causes dissection. Two cases of spontaneous coronary artery dissection are described, together with a brief review of previously published cases. Based on this review, we conclude that periadventitial inflammation is reactive, rather than primary, in nature.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aneurysm, Dissecting / etiology
  • Aneurysm, Dissecting / pathology*
  • Arteritis / complications
  • Arteritis / pathology
  • Coronary Aneurysm / etiology
  • Coronary Aneurysm / pathology*
  • Female
  • Granuloma / pathology
  • Humans
  • Middle Aged