Do endotoxins devoid of 3-deoxy-D-manno-2-octulosonic acid exist?

Biochem Biophys Res Commun. 1987 Mar 30;143(3):845-7. doi: 10.1016/0006-291x(87)90326-3.


After treatment with aqueous, 50% hydrofluoric acid, a well-known dephosphorylating agent, the presence of 3-deoxy-D-manno-2-octulosonic acid (KDO), an essential and characteristic constituent of endotoxins, can be readily demonstrated in reportedly KDO-deficient bacterial lipopolysaccharides.

MeSH terms

  • Endotoxins / analysis*
  • Lipopolysaccharides / analysis
  • Sugar Acids / analysis*


  • Endotoxins
  • Lipopolysaccharides
  • Sugar Acids
  • 2-keto-3-deoxyoctonate