Approximately optimal one-parameter boundaries for group sequential trials

Biometrics. 1987 Mar;43(1):193-9.


We present a class of group sequential tests, indexed by a single parameter, that yields approximately optimal results. We also provide tables of key values to help in the design of group sequential tests that meet selected specifications.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Clinical Trials as Topic / methods*
  • Humans
  • Statistics as Topic / methods*