Summary: Every protein family has a set of characteristic secondary structures. However, due to individual variations, a single structure is not enough to represent the whole family. OverProt can create a secondary structure consensus, showing the general fold of the family as well as its variation. Our server provides precomputed results for all CATH superfamilies and user-defined computations, visualized by an interactive viewer, which shows the secondary structure element type, length, frequency of occurrence, spatial variability and β-connectivity.
Availability and implementation: OverProt Server is freely available at https://overprot.ncbr.muni.cz.
Supplementary information: Supplementary data are available at Bioinformatics online.
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